Abstract: . . .  proaches in gene mapping in complex human diseases. New York: Wiley-Liss, 1998: 1-16. 42 Barnes PJ. New directions in allergic diseases: mechanism-based anti-inflam- matory therapies. J Allergy Clin Immunol 2000; 106(1 Pt 1):5-16. 43 Baier LJ, Permana PA, Yang X, Pratley RE, Hanson RL, Shen GQ et al. A cal- pain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance. J Clin Invest 2000; 106(7):R69-R73. 44 Panhuysen CI. Genetics and natural history of astma (thesis). 1996. 45 Wiener AS, Zieve I, Fries JH. The inheritance of allergic disease. Ann Eugenics 1936; 7:141-162. 46 Xu J, Postma DS, Howard TD, Koppelman GH, Zheng SL, Stine OC et al. Major genes regulating total serum immunoglobulin E levels in families with asth- ma. Am J Hum Genet 2000; 67(5):1163-1173. 47 Te Meerman GJ, Van der Meulen MA, Sandkuyl L. Perspecitives of identity by descent (IBD) mapping in founder . . .
. . .  Roche WR, Walls AF. The bronchial epithe- lium as a key regulator of airway inflammation and airway remodelling in asthma. Clin Exp Allergy 1999; 29, Supplement 2:90-95. 32 Busse W, Elias J, Sheppard D, Banks-Schlegel S. Airway remodeling and repair. Am J Respir Crit Care Med 1999; 160(3):1035-1042. 24 Genetics of asthma and atopy Page 25 33 Martinez FD, Holt PG. Role of microbial burden in aetilogy of allergy and asthma. Lancet 1999; 354 (Suppl II):12-15. 34 Corry DB, Kheradmand F. Induction and regulation of the IgE response. Na- ture 1999; 402(6760 Suppl):B18-B23. 35 Watson JD, Crick FHC. Molecular structure of nucleic acids. A structure for de- oxyribose nucleic acid. Nature 1953; 191:737-738. 36 Venter JC, Adams MD, Myers EW, Li PW, Mural RJ, Sutton GG et al. The se- quence of the human genome. Science 2001; 291(5507):1304-1351. 37 International human genome . . .
. . .  Perspecitives of identity by descent (IBD) mapping in founder populations. Clin Exp Allergy 1995; 25(Supplement 2):97-102. 48 McPeek MS, Strahs A. Assessment of linkage disequilibrium by the decay of haplotype sharing, with application to fine-scale genetic mapping. Am J Hum Genet 1999; 65(3):858-875. 49 Lam JC, Roeder K, Devlin B. Haplotype fine mapping by evolutionary trees. Am J Hum Genet 2000; 66(2):659-673. 50 Service SK, Lang DW, Freimer NB, Sandkuijl LA. Linkage-disequilibrium map- ping of disease genes by reconstruction of ancestral haplotypes in founder populations. Am J Hum Genet 1999; 64(6):1728-1738. Introduction 25 Page 26  . . .
--3000,3,500,2976,45293