Abstract: . . .  intolerance Course influenced by environmental or emotional factors Page 19 15 SCORAD The Severity Scoring of Atopic Dermatitis (SCORAD) 30 is a standardized method for assessing the eczema , taking into account the extent and severity as well as the consequences of the skin disorder (degree of pruritus and sleeping disorder assessed by the parents). According to this classification, the eczema can be . . .
. . .  reactivity. Consequently, the tests may be considered an excellent means of ruling out IgE-mediated food allergies, but are only suggestive of the presence of clinical food allergy. 58-60 Approximately 85% of children with eczema have elevated serum IgE, and about 85% of these have specific IgE antibodies to food and inhalant allergens. 19 Page 27 23 Skin prick test The SPT method, used extensively . . .
. . .  used. Therefore different cut-off values are likely to be required for different subpopulations of children, and the results of different studies should be compared with great caution. 56 Specific IgE in sera RAST and similar qualitative in vitro assays provide suggestive evidence of IgE- mediated food allergy, but these assays are giving way to quantitative measurements of food-specific IgE antibodies (e.g. Pharmacia CAP system specific IgE, FEIA  . . .
. . .  specific IgE, FEIA ), which have been shown to be more predictive of symptomatic IgE-mediated food allergy. 39 Determination of food-specific IgE/total IgE gives similar results to the determination of food-specific IgE alone, making it an unnecessary effort to calculate the r . . .
. . .  these assays are giving way to quantitative measurements of food-specific IgE antibodies (e.g. Pharmacia CAP system specific IgE, FEIA ), which have been shown to be more predictive of symptomatic IgE-mediated food allergy. 39 Determination of food-specific IgE/total IgE gives similar results to the determination of food-specific IgE alone, making it an unnecessary effort to calculate the r . . .
. . .  60,61,71,72 - Sensitivity 87-98% - Specificity 53-71% - PPA 40-85% - NPA 85-96% Cutaneous reactivity varies with age and the clinical context. The wheal size in positive SPT results is smaller in young infants. 73 The PPA at cut-off level >3 mm in Page 29 25 SPT to egg has been shown to differ between 40% in children > 3 years and 80% in children < 3 years.  . . .
--3000,6,250,3227,63925